CHMP1B and VPS4B

Data Source:
HPRD (in vitro)

		CHMP1B	VPS4B
Description		charged multivesicular body protein 1B	vacuolar protein sorting 4 homolog B
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GO Annotations	Cellular Component	ESCRT III Complex Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Membrane Coat Midbody Late Endosome Membrane Extracellular Exosome	Spindle Pole Nucleus Cytoplasm Endosome Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Protein Domain Specific Binding Identical Protein Binding	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding
	Biological Process	Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Cell Division Midbody Abscission Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Potassium Ion Transport Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Viral Release From Host Cell Cholesterol Transport Cytoplasmic Microtubule Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Process Regulation Of Viral Process Microtubule Severing Protein Depolymerization Negative Regulation Of Cell Death Late Endosomal Microautophagy Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Life Cycle ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)
Interacting Genes		19 interacting genes: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN MITD1 PICK1 RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B VTA1	8 interacting genes: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 KATNAL1 VPS4A ZFYVE19
Entrez ID		57132	9525
HPRD ID		12106	15653
Ensembl ID		ENSG00000255112	ENSG00000119541
Uniprot IDs		Q7LBR1	A0A024R2C5 O75351
PDB IDs		3EAB 3JC1 4TXQ 4TXR 6E8G 6TZ4 6TZ5 6TZ9	1WR0 1XWI 2CPT 2JQH 2JQK 4U7Y
Enriched GO Terms of Interacting Partners?
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