VPS4B and ZFYVE19

Data Source:
BioGRID (two hybrid, two hybrid, biochemical)

		VPS4B	ZFYVE19
Description		vacuolar protein sorting 4 homolog B	zinc finger FYVE-type containing 19
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Endosome Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Exosome Flemming Body	Cytoplasm Centrosome Midbody Cleavage Furrow Flemming Body
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Potassium Ion Transport Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Viral Release From Host Cell Cholesterol Transport Cytoplasmic Microtubule Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Process Regulation Of Viral Process Microtubule Severing Protein Depolymerization Negative Regulation Of Cell Death Late Endosomal Microautophagy Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Life Cycle ESCRT III Complex Disassembly	Abscission Negative Regulation Of Cytokinesis Mitotic Cytokinesis Checkpoint Cell Division
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)	Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061)
Interacting Genes		8 interacting genes: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 KATNAL1 VPS4A ZFYVE19	10 interacting genes: AXIN1 CAPN7 CCHCR1 DPY30 HTT MITD1 TRIM55 TRIM63 VPS4B ZDHHC17
Entrez ID		9525	84936
HPRD ID		15653	15731
Ensembl ID		ENSG00000119541	ENSG00000166140
Uniprot IDs		A0A024R2C5 O75351	Q96K21
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK 4U7Y
Enriched GO Terms of Interacting Partners?
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