CAND1 and LNPK

Data Source:
BioGRID (pull down, biochemical, pull down)

		CAND1	LNPK
Description		cullin associated and neddylation dissociated 1	lunapark, ER junction formation factor
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Cullin-RING Ubiquitin Ligase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane
	Molecular Function	Protein Binding TBP-class Protein Binding	Identical Protein Binding Metal Ion Binding
	Biological Process	Cellular Iron Ion Homeostasis SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Neutrophil Degranulation Post-translational Protein Modification Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly	Endoplasmic Reticulum Organization Blood Coagulation Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Embryonic Digit Morphogenesis Limb Development Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Maintenance Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Pathways		Neutrophil degranulation Neddylation Iron uptake and transport
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Expressive vocabulary in infants ( 25226531) HDL cholesterol levels ( 32203549) Hippocampal atrophy ( 19668339) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		18 interacting genes: CA9 CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 DCUN1D2 DCUN1D4 DCUN1D5 DUX4 LNPK MTNR1A RBX1 SKP1 SRPK2 UBE2M	12 interacting genes: ANXA1 CAND1 CHMP1A KLHL12 LMO3 NOC4L PAX6 PLIN3 SYP UBC UBE2D1 YIF1A
Entrez ID		55832	80856
HPRD ID		06983	13886
Ensembl ID		ENSG00000111530	ENSG00000144320
Uniprot IDs		Q86VP6	B7Z829 Q9C0E8
PDB IDs		1U6G 4A0C
Enriched GO Terms of Interacting Partners?
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