LNPK and KLHL12

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		LNPK	KLHL12
Description		lunapark, ER junction formation factor	kelch like family member 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Identical Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Endoplasmic Reticulum Organization Blood Coagulation Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Embryonic Digit Morphogenesis Limb Development Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Maintenance Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization	Protein Monoubiquitination Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Degradation of DVL
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: ANXA1 CAND1 CHMP1A KLHL12 LMO3 NOC4L PAX6 PLIN3 SYP UBC UBE2D1 YIF1A	62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL1 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4
Entrez ID		80856	59349
HPRD ID		13886	13925
Ensembl ID		ENSG00000144320	ENSG00000117153
Uniprot IDs		B7Z829 Q9C0E8	Q53G59 Q9H7R2
PDB IDs			2VPJ 6TTK 6V7O
Enriched GO Terms of Interacting Partners?
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