SPATA7 and PTF1A

Data Source:
BioGRID (two hybrid)

		SPATA7	PTF1A
Description		spermatogenesis associated 7	pancreas associated transcription factor 1a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Axoneme Microtubule Cytoskeleton Photoreceptor Connecting Cilium Ciliary Basal Body Rod Photoreceptor Outer Segment Photoreceptor Distal Connecting Cilium	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Visual Perception Photoreceptor Cell Maintenance Response To Stimulus Protein Localization To Photoreceptor Outer Segment Protein Localization To Photoreceptor Connecting Cilium	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development
Pathways			Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases		Leber congenital amaurosis (LCR) Retinitis pigmentosa (RP)	Permanent neonatal diabetes mellitus (PNDM)
GWAS		Attention deficit hyperactivity disorder ( 30563984) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Coronary artery calcification ( 23870195) Estimated glomerular filtration rate ( 31152163 31451708) Information processing speed ( 21130836)	Type 2 diabetes ( 32499647)
Interacting Genes		3 interacting genes: APP HSPB1 PTF1A	11 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10
Entrez ID		55812	256297
HPRD ID		15431	09526
Ensembl ID		ENSG00000042317	ENSG00000168267
Uniprot IDs		Q9P0W8 V9HVY9	Q7RTS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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