PTF1A and SPATA7

Data Source:
BioGRID (two hybrid)

		PTF1A	SPATA7
Description		pancreas associated transcription factor 1a	spermatogenesis associated 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Nucleoplasm Mitochondrion Cytosol Axoneme Microtubule Cytoskeleton Photoreceptor Connecting Cilium Ciliary Basal Body Rod Photoreceptor Outer Segment Photoreceptor Distal Connecting Cilium
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development	Microtubule Cytoskeleton Organization Visual Perception Photoreceptor Cell Maintenance Response To Stimulus Protein Localization To Photoreceptor Outer Segment Protein Localization To Photoreceptor Connecting Cilium
Pathways		Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases		Permanent neonatal diabetes mellitus (PNDM)	Leber congenital amaurosis (LCR) Retinitis pigmentosa (RP)
GWAS		Type 2 diabetes ( 32499647)	Attention deficit hyperactivity disorder ( 30563984) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Coronary artery calcification ( 23870195) Estimated glomerular filtration rate ( 31152163 31451708) Information processing speed ( 21130836)
Interacting Genes		11 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	3 interacting genes: APP HSPB1 PTF1A
Entrez ID		256297	55812
HPRD ID		09526	15431
Ensembl ID		ENSG00000168267	ENSG00000042317
Uniprot IDs		Q7RTS3	Q9P0W8 V9HVY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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