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ZNF446 and FRS3
Data Source:
BioGRID
(two hybrid)
ZNF446
FRS3
Description
zinc finger protein 446
fibroblast growth factor receptor substrate 3
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Extracellular Space
Nucleus
Plasma Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
Generic Transcription Pathway
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Uric acid clearance (
28095793
)
Menarche (age at onset) (
25231870
)
Interacting Genes
60 interacting genes:
ACTN2
ANKRD1
CCNK
COPS2
CYSRT1
DGCR6
DGCR6L
EHMT2
EVI5
FHL5
FRMD8
FRS3
GOLGA6L9
INCA1
KIFC3
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP3-1
LNX1
LZTS2
MAGOHB
MDFI
NBPF19
NOTCH2NLA
PGBD1
PIN1
REL
SCAND1
SIVA1
SUFU
TAX1BP1
TRIM27
UBE2I
UBE3A
ZKSCAN4
ZKSCAN7
ZNF165
ZNF18
ZNF232
ZNF24
ZNF263
ZNF396
ZNF397
ZNF483
ZNF496
ZSCAN12
ZSCAN16
ZSCAN18
ZSCAN21
ZSCAN22
ZSCAN23
ZSCAN29
ZSCAN30
ZSCAN32
ZSCAN9
111 interacting genes:
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C11orf1
C11orf45
C19orf54
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PPP1R32
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SCNM1
SH2B1
SLAIN1
SLC22A18AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
Entrez ID
55663
10817
HPRD ID
07934
06373
Ensembl ID
ENSG00000083838
ENSG00000137218
Uniprot IDs
Q8NDK2
Q9NWS9
Q9UFF2
A0A140VJJ7
O43559
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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