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FRS3 and DMRT3
Data Source:
BioGRID
(two hybrid)
FRS3
DMRT3
Description
fibroblast growth factor receptor substrate 3
doublesex and mab-3 related transcription factor 3
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Chromatin
Nucleus
Molecular Function
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
MAPK Cascade
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Sex Differentiation
Adult Walking Behavior
Transmission Of Nerve Impulse
Ventral Spinal Cord Interneuron Specification
Regulation Of Odontogenesis Of Dentin-containing Tooth
Male Sex Differentiation
Pathways
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS
Menarche (age at onset) (
25231870
)
Dupuytren's disease (
28886342
)
Major depressive disorder (
23377640
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
Response to Homoharringtonine (cytotoxicity) (
25628645
)
Interacting Genes
111 interacting genes:
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C11orf1
C11orf45
C19orf54
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PPP1R32
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SCNM1
SH2B1
SLAIN1
SLC22A18AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
86 interacting genes:
AKAP8L
ASPG
ATN1
ATP6V0D1
C11orf1
CCNDBP1
CYSRT1
FHL3
FHL5
FOXN1
FRS3
GPSM1
GRN
HSF2BP
INCA1
KHDRBS3
KPRP
KRT31
KRT34
KRT35
KRT36
KRT38
KRT40
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP19-5
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP3-3
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
LASP1
LMO2
MDFI
MEOX2
MGAT5B
MID2
MTUS2
MYOZ3
NBPF19
NFKBID
NHLRC4
NOTCH2NLA
OIP5
PFDN5
PLEKHF2
PLSCR1
PRDM14
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMA3
PSME3
RBPMS
REL
RFX6
RUSC1
SAT1
SPAG8
TCF4
TLE5
TRAF1
TRIM23
TRIM27
TRIP6
TSC1
TTC19
UBASH3B
USP54
WWOX
YPEL3
ZFY
ZMYND12
ZNF438
Entrez ID
10817
58524
HPRD ID
06373
16827
Ensembl ID
ENSG00000137218
ENSG00000064218
Uniprot IDs
A0A140VJJ7
O43559
Q9NQL9
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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