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OTUB1 and RNF126
Data Source:
BioGRID
(two hybrid)
OTUB1
RNF126
Description
OTU deubiquitinase, ubiquitin aldehyde binding 1
ring finger protein 126
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
NEDD8-specific Protease Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Adaptive Immune Response
DNA Repair
Cellular Response To DNA Damage Stimulus
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K48-linked Deubiquitination
Negative Regulation Of Histone H2A K63-linked Ubiquitination
Negative Regulation Of Double-strand Break Repair
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Retrograde Transport, Endosome To Golgi
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System
Pathways
Ub-specific processing proteases
Ovarian tumor domain proteases
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Arterial stiffness (
31070453
)
Arterial stiffness index (
31235810
)
Pulse pressure (
30578418
)
Interacting Genes
55 interacting genes:
ACVR1
ACVR1B
ANXA1
ANXA7
AURKA
BIRC2
BMPR1A
BMPR1B
CDKN1A
CPEB2
CSNK2A1
ECT2
ESR1
FOXM1
H2AX
IL1RL2
KDM1A
MAPT
NEDD8
PJA1
RFFL
RHOA
RNF126
RNF128
SLC7A11
SMAD2
SMAD3
SMAD4
SMAD9
SNAI1
TGFBR1
TP53
TRAF6
TRIM54
TRIM55
TRIM63
TSC22D1
TTR
UBA6
UBC
UBD
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2N
UBE2S
UBE2V2
UBE2Z
UBE4B
USP15
USP21
USP28
39 interacting genes:
AICDA
BAG6
CDKN1A
CENPP
CSNK2B
E2F1
EGFR
FXN
HMGCL
MAP3K1
MDM2
MIEN1
NUDT3
OTUB1
OTUB2
PLK1
PSMF1
RBX1
RNF168
SNUPN
TRIM11
TRIM23
TRIM26
TRIM52
TSG101
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2N
UBL3
UBL4A
USP15
USP2
XRCC5
XRCC6
Entrez ID
55611
55658
HPRD ID
08493
11501
Ensembl ID
ENSG00000167770
ENSG00000070423
Uniprot IDs
B3KUV5
Q96FW1
A0A024R206
A8K0Q1
Q9BV68
PDB IDs
2ZFY
3VON
4DDG
4DDI
4DHZ
4I6L
4LDT
2N9O
2N9P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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