Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
OTUB1 and UBE2V2
Data Source:
BioGRID
(pull down)
OTUB1
UBE2V2
Description
OTU deubiquitinase, ubiquitin aldehyde binding 1
ubiquitin conjugating enzyme E2 V2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
UBC13-MMS2 Complex
Extracellular Exosome
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
NEDD8-specific Protease Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
Protein Binding
Biological Process
Adaptive Immune Response
DNA Repair
Cellular Response To DNA Damage Stimulus
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K48-linked Deubiquitination
Negative Regulation Of Histone H2A K63-linked Ubiquitination
Negative Regulation Of Double-strand Break Repair
Protein Polyubiquitination
DNA Double-strand Break Processing
Regulation Of DNA Repair
Postreplication Repair
Double-strand Break Repair Via Nonhomologous End Joining
Positive Regulation Of Neuron Projection Development
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Error-free Postreplication DNA Repair
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of DNA Repair
Positive Regulation Of Synapse Assembly
Protein K63-linked Ubiquitination
Pathways
Ub-specific processing proteases
Ovarian tumor domain proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Formation of Incision Complex in GG-NER
G2/M DNA damage checkpoint
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Height (
31562340
)
Interacting Genes
55 interacting genes:
ACVR1
ACVR1B
ANXA1
ANXA7
AURKA
BIRC2
BMPR1A
BMPR1B
CDKN1A
CPEB2
CSNK2A1
ECT2
ESR1
FOXM1
H2AX
IL1RL2
KDM1A
MAPT
NEDD8
PJA1
RFFL
RHOA
RNF126
RNF128
SLC7A11
SMAD2
SMAD3
SMAD4
SMAD9
SNAI1
TGFBR1
TP53
TRAF6
TRIM54
TRIM55
TRIM63
TSC22D1
TTR
UBA6
UBC
UBD
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2N
UBE2S
UBE2V2
UBE2Z
UBE4B
USP15
USP21
USP28
33 interacting genes:
BCL10
DZIP3
EGFR
HLTF
IGSF21
LNX1
LRIF1
MALT1
MKRN3
MOB4
MUL1
OTUB1
RC3H1
RC3H2
RFFL
RNF144A
RNF2
RNF8
SHPRH
SIAH1
SIAH2
STUB1
SUV39H2
TP53
TRAF2
TRIM21
TRIM5
TRIM54
TRIM63
UBC
UBE2N
XIAP
ZNRF1
Entrez ID
55611
7336
HPRD ID
08493
04300
Ensembl ID
ENSG00000167770
ENSG00000169139
Uniprot IDs
B3KUV5
Q96FW1
A0M8W4
Q15819
PDB IDs
2ZFY
3VON
4DDG
4DDI
4DHZ
4I6L
4LDT
1J74
1J7D
1ZGU
3VON
4NR3
4NRG
4NRI
4ONL
4ONM
4ONN
4ORH
5AIT
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?