RNF126 and MIEN1

Data Source:
BioGRID (two hybrid)

		RNF126	MIEN1
Description		ring finger protein 126	migration and invasion enhancer 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Cytosol Plasma Membrane Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Centriolar Satellite
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Population Proliferation Retrograde Transport, Endosome To Golgi Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System	Apoptotic Process Response To Selenium Ion Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Arterial stiffness ( 31070453) Arterial stiffness index ( 31235810) Pulse pressure ( 30578418)	Asthma ( 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)
Interacting Genes		39 interacting genes: AICDA BAG6 CDKN1A CENPP CSNK2B E2F1 EGFR FXN HMGCL MAP3K1 MDM2 MIEN1 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 RNF168 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2E3 UBE2N UBL3 UBL4A USP15 USP2 XRCC5 XRCC6	14 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32
Entrez ID		55658	84299
HPRD ID		11501	12681
Ensembl ID		ENSG00000070423	ENSG00000141741
Uniprot IDs		A0A024R206 A8K0Q1 Q9BV68	J3KTI2 Q9BRT3
PDB IDs		2N9O 2N9P	2LJK
Enriched GO Terms of Interacting Partners?
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