NAGK and LMO1

Data Source:
BioGRID (two hybrid)

		NAGK	LMO1
Description		N-acetylglucosamine kinase	LIM domain only 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	Protein Binding Metal Ion Binding
	Biological Process	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Synthesis of UDP-N-acetyl-glucosamine	RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs		N-Acetylglucosamine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Alcohol consumption ( 23743675) Body mass index ( 31888951 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Diastolic blood pressure ( 27618447) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Height ( 31562340) Malaria ( 31844061) Neuroblastoma ( 22941191 21124317) Offspring birth weight ( 31043758) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 27618447)
Interacting Genes		33 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	122 interacting genes: ABI1 ABI2 ADAMTSL4 AKAP9 AKNA ASB15 BANP BCAS2 BCL11A BHLHB9 BIVM BLZF1 BNC2 BYSL CARD9 CBY2 CCDC33 CCDC88B CDCA7L CDX4 CEP170P1 CEP44 CEP57L1 CHCHD3 DDIT4L ERBIN EVI5 FBXO16 GABPB1 GAS8 GATA3 GOLGA2 GPATCH2L HDX HGS HMBOX1 HMG20A HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IKZF3 ISY1 KANK2 KCTD1 KIAA1328 KRBOX4 KRT16 KRT40 KRT75 LDB1 LDB2 LPXN LYL1 LZTS1 LZTS2 MAD1L1 MBD3L1 MEOX2 MISP MSS51 NAGK NDUFA7 NHLH1 NTAQ1 NUTM1 PHC2 PICK1 POLR3GL PPP1R13B PRDM6 PSMB1 PTPN3 PXN RBBP8 RCN1 REL SAXO1 SNTA1 SOX5 SPG21 SYTL4 TADA2A TAL1 TAL2 TASOR2 TCF4 TCP10L TFIP11 TLE5 TRIM27 TRIM35 TRIM54 TSC22D4 UFSP2 UHMK1 UNKL UTP14A VBP1 WASHC1 ZBTB43 ZBTB8B ZCCHC12 ZFP90 ZNF143 ZNF177 ZNF19 ZNF219 ZNF24 ZNF354C ZNF417 ZNF460 ZNF511 ZNF526 ZNF559-ZNF177 ZNF620 ZNF641 ZNF688 ZNF76 ZNF84
Entrez ID		55577	4004
HPRD ID		08441	01738
Ensembl ID		ENSG00000124357	ENSG00000166407
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	E9PK83 P25800
PDB IDs		2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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