LMO1 and ZFP90

Data Source:
BioGRID (two hybrid)

		LMO1	ZFP90
Description		LIM domain only 1	ZFP90 zinc finger protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation Regulation Of Hematopoietic Stem Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs	Generic Transcription Pathway
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Body mass index ( 31888951 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Diastolic blood pressure ( 27618447) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Height ( 31562340) Malaria ( 31844061) Neuroblastoma ( 22941191 21124317) Offspring birth weight ( 31043758) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 27618447)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HIV-1 viral setpoint ( 22174851) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Systemic lupus erythematosus ( 27399966 28714469) Ulcerative colitis ( 28067908 23128233 21297633)
Interacting Genes		122 interacting genes: ABI1 ABI2 ADAMTSL4 AKAP9 AKNA ASB15 BANP BCAS2 BCL11A BHLHB9 BIVM BLZF1 BNC2 BYSL CARD9 CBY2 CCDC33 CCDC88B CDCA7L CDX4 CEP170P1 CEP44 CEP57L1 CHCHD3 DDIT4L ERBIN EVI5 FBXO16 GABPB1 GAS8 GATA3 GOLGA2 GPATCH2L HDX HGS HMBOX1 HMG20A HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IKZF3 ISY1 KANK2 KCTD1 KIAA1328 KRBOX4 KRT16 KRT40 KRT75 LDB1 LDB2 LPXN LYL1 LZTS1 LZTS2 MAD1L1 MBD3L1 MEOX2 MISP MSS51 NAGK NDUFA7 NHLH1 NTAQ1 NUTM1 PHC2 PICK1 POLR3GL PPP1R13B PRDM6 PSMB1 PTPN3 PXN RBBP8 RCN1 REL SAXO1 SNTA1 SOX5 SPG21 SYTL4 TADA2A TAL1 TAL2 TASOR2 TCF4 TCP10L TFIP11 TLE5 TRIM27 TRIM35 TRIM54 TSC22D4 UFSP2 UHMK1 UNKL UTP14A VBP1 WASHC1 ZBTB43 ZBTB8B ZCCHC12 ZFP90 ZNF143 ZNF177 ZNF19 ZNF219 ZNF24 ZNF354C ZNF417 ZNF460 ZNF511 ZNF526 ZNF559-ZNF177 ZNF620 ZNF641 ZNF688 ZNF76 ZNF84	23 interacting genes: ABI2 ATPAF2 BOLA2 BOLA2B CCNC CPNE7 ENKD1 EXOSC5 GCC1 GLYCTK GTPBP3 HOXC8 LMO1 LONRF1 MALSU1 MLH1 NEK6 PRKAB2 RUNX1T1 TBC1D22B TDRKH TEKT4 TRAPPC6A
Entrez ID		4004	146198
HPRD ID		01738	18729
Ensembl ID		ENSG00000166407	ENSG00000184939
Uniprot IDs		E9PK83 P25800	J3QKQ8 Q8TF47
PDB IDs
Enriched GO Terms of Interacting Partners?
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