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NAGK and CEP43
Data Source:
BioGRID
(two hybrid)
NAGK
CEP43
Description
N-acetylglucosamine kinase
centrosomal protein 43
Image
GO Annotations
Cellular Component
Cytosol
Extracellular Exosome
Nucleus
Centrosome
Centriole
Cytosol
Cell Projection
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
ATP Binding
N-acetylglucosamine Kinase Activity
Protein Binding
Protein Kinase Binding
Protein Tyrosine Kinase Inhibitor Activity
Protein Homodimerization Activity
Biological Process
N-acetylglucosamine Metabolic Process
UDP-N-acetylglucosamine Biosynthetic Process
N-acetylmannosamine Metabolic Process
N-acetylneuraminate Catabolic Process
Carbohydrate Phosphorylation
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Cell Population Proliferation
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Microtubule Anchoring
Negative Regulation Of Protein Tyrosine Kinase Activity
Ciliary Basal Body-plasma Membrane Docking
Pathways
Synthesis of UDP-N-acetyl-glucosamine
Signaling by cytosolic FGFR1 fusion mutants
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Signaling by FGFR1 in disease
AURKA Activation by TPX2
Drugs
N-Acetylglucosamine
Diseases
GWAS
Blood protein levels (
30072576
29875488
28240269
)
Erythema nodosum in inflammatory bowel disease (
24487271
)
Interacting Genes
33 interacting genes:
ACTR10
ANKRD1
CCDC158
CDKN2C
CEP43
DACH1
DCP2
DYNC1I1
GNPNAT1
LACTB2
LENG1
LMO1
LNX1
LNX2
LSM8
MEOX1
MTHFD2
NTAQ1
PJA1
PKM
PPHLN1
REL
SDCBP
SF3B3
SMAD2
SMAD9
SPRED1
SRPK2
STK16
SYNE4
TCF12
TNNT1
WDR82
5 interacting genes:
CEP19
NAGK
PPP2R1B
S100A6
VASP
Entrez ID
55577
11116
HPRD ID
08441
10392
Ensembl ID
ENSG00000124357
ENSG00000213066
Uniprot IDs
A0A384N6G7
C9JEV6
Q9UJ70
A0A087WV25
B4DH64
O95684
PDB IDs
2CH5
2CH6
2D68
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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