CEP43 and CEP19

Data Source:
BioGRID (two hybrid)

		CEP43	CEP19
Description		centrosomal protein 43	centrosomal protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Centriole Cytosol Cell Projection Perinuclear Region Of Cytoplasm	Spindle Pole Cytoplasm Centrosome Centriole Cilium Ciliary Basal Body
	Molecular Function	Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity Ciliary Basal Body-plasma Membrane Docking	Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
Pathways		Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738)
Interacting Genes		5 interacting genes: CEP19 NAGK PPP2R1B S100A6 VASP	50 interacting genes: AK4 ANAPC15 C4orf19 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CEP350 CEP43 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2A RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81
Entrez ID		11116	84984
HPRD ID		10392	17488
Ensembl ID		ENSG00000213066	ENSG00000174007
Uniprot IDs		A0A087WV25 B4DH64 O95684	Q96LK0
PDB IDs		2D68
Enriched GO Terms of Interacting Partners?
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