HEMGN and MCC

Data Source:
BioGRID (two hybrid)

		HEMGN	MCC
Description		hemogen	MCC regulator of WNT signaling pathway
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Multicellular Organism Development Cell Differentiation Regulation Of Osteoblast Differentiation	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Quantitative traits ( 19197348) Thyroid cancer (Papillary, radiation-related) ( 20350937)	Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549)
Interacting Genes		34 interacting genes: AURKA AXIN2 BCL10 BUB1 CDH1 CTBP1 CTBP2 DCC DLC1 EGFR ENO1 EP300 FBXW7 FLCN GATA1 H2AC6 HMGA1 HSPA1A KAT6A KRAS MCC MED17 MLH3 NRAS ODC1 PTPRJ SMAD4 SP100 SRC THAP11 TLR2 TRAF3 WHRN ZBTB1	79 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792
Entrez ID		55363	4163
HPRD ID		17100	01157
Ensembl ID		ENSG00000136929	ENSG00000171444
Uniprot IDs		A0A024R162 Q9BXL5	P23508
PDB IDs			6MTU 6MTV
Enriched GO Terms of Interacting Partners?
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