HEMGN and THAP11

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HEMGN	THAP11
Description		hemogen	THAP domain containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromatin Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Multicellular Organism Development Cell Differentiation Regulation Of Osteoblast Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Quantitative traits ( 19197348) Thyroid cancer (Papillary, radiation-related) ( 20350937)	Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		34 interacting genes: AURKA AXIN2 BCL10 BUB1 CDH1 CTBP1 CTBP2 DCC DLC1 EGFR ENO1 EP300 FBXW7 FLCN GATA1 H2AC6 HMGA1 HSPA1A KAT6A KRAS MCC MED17 MLH3 NRAS ODC1 PTPRJ SMAD4 SP100 SRC THAP11 TLR2 TRAF3 WHRN ZBTB1	20 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52
Entrez ID		55363	57215
HPRD ID		17100	11629
Ensembl ID		ENSG00000136929	ENSG00000168286
Uniprot IDs		A0A024R162 Q9BXL5	Q96EK4
PDB IDs			2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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