MCC and CCDC185

Data Source:
BioGRID (two hybrid)

		MCC	CCDC185
Description		MCC regulator of WNT signaling pathway	coiled-coil domain containing 185
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549)
Interacting Genes		79 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792	49 interacting genes: AMOTL2 BACH2 CADPS CALCOCO2 CBY2 CCDC136 CCDC85B CDR2L CEP44 CEP57 EVI5 EVI5L FAM161A GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HSF2BP IKZF1 ISY1-RAB43 KRT15 KRT27 KRT35 KRT40 KRTAP10-7 KRTAP4-12 KXD1 LURAP1 MAGEA11 MAGEA2 MAGEA2B MAGEA6 MCC MDFI MID2 MKRN3 MTUS2 NAP1L2 NUTM1 PDLIM7 PKNOX2 PPP1R12C SPRED1 SPTA1 TBC1D1 TRAF1 TRIM27 VPS52 ZRANB1
Entrez ID		4163	164127
HPRD ID		01157	08761
Ensembl ID		ENSG00000171444	ENSG00000178395
Uniprot IDs		P23508	Q8N715
PDB IDs		6MTU 6MTV
Enriched GO Terms of Interacting Partners?
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