SYNJ2BP and CD79A

Data Source:
BioGRID (two hybrid)

		SYNJ2BP	CD79A
Description		synaptojanin 2 binding protein	CD79a molecule
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways			CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1	181 interacting genes: ADIPOQ AGTRAP ALG10 ALG10B ALG3 APOD AQP1 AQP3 ATP6V0C BCL2L2 BET1 BLK BLNK BRICD5 BTN2A2 C14orf180 C1GALT1 C2CD2L C4orf3 CCDC167 CD19 CD5 CD79B CDIPT CLDN1 CLN6 CMTM5 CMTM7 CNIH1 CNIH3 COL4A5 CTSA CTXN3 CYB561 CYB561A3 CYB561D2 CYB5B DEFB127 DOLK EDDM3B EMC6 EMP1 EMP3 FA2H FAM241B FANCA FATE1 FAXDC2 FCAR FDFT1 FFAR3 FKBP8 FUNDC2 FXYD3 FYN GALNT15 GIMAP1 GJB1 GPR42 HACD4 HCLS1 HMOX1 HMOX2 IER3 IGHM INSIG2 ITGAM JAGN1 JCHAIN LAMB1 LCK LEPROTL1 LHFPL5 LPAR3 LTC4S LYN MALL MARCHF2 MFF MFSD12 MFSD5 MFSD6 MGLL MMD2 MOSPD3 MS4A13 MYADM MYADML2 NAT8 NEU1 NINJ2 NIPAL3 NKG7 ORMDL2 OTOP2 PGAP2 PIGR PKMYT1 PLP2 PLPP6 PLPPR2 PNLIPRP1 PRAF2 PTCH1 PTPN6 REEP6 RHO RTP2 SACM1L SEC22B SERP1 SFTPC SLC13A4 SLC13A5 SLC16A12 SLC16A13 SLC30A2 SLC35B1 SLC35B4 SLC38A1 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC46A3 SLC66A2 SLC6A12 SLC7A1 SMCO4 SMIM3 STRIT1 STX12 STX3 STX8 SYK SYNJ2BP TECR THBD TM4SF19 TM4SF4 TMBIM6 TMEM107 TMEM11 TMEM128 TMEM140 TMEM147 TMEM14B TMEM176A TMEM187 TMEM19 TMEM218 TMEM222 TMEM229B TMEM239 TMEM243 TMEM254 TMEM262 TMEM42 TMEM86A TMEM86B TMPPE TNFRSF10C TRAM1L1 TRARG1 TSNARE1 TSPAN2 TSPO2 UBE2J1 UBIAD1 UNC93B1 VAMP3 VAPA VAPB VTI1B WFDC2 WFS1 YIF1A YIPF4 YIPF6 ZDHHC15 ZDHHC22
Entrez ID		55333	973
HPRD ID		15455	00203
Ensembl ID		ENSG00000213463	ENSG00000105369
Uniprot IDs		A0A024R670 P57105	P11912
PDB IDs		2ENO 2JIK 2JIN	1CV9
Enriched GO Terms of Interacting Partners?
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