SYNJ2BP and ELOVL7

Data Source:
BioGRID (two hybrid)

		SYNJ2BP	ELOVL7
Description		synaptojanin 2 binding protein	ELOVL fatty acid elongase 7
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways			Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)
Interacting Genes		33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1	12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1
Entrez ID		55333	79993
HPRD ID		15455	18700
Ensembl ID		ENSG00000213463	ENSG00000164181
Uniprot IDs		A0A024R670 P57105	A1L3X0 D6RHD0
PDB IDs		2ENO 2JIK 2JIN	6Y7F
Enriched GO Terms of Interacting Partners?
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