RNF152 and RRAGA

Data Source:
BioGRID (pull down, affinity chromatography technology)

		RNF152	RRAGA
Description		ring finger protein 152	Ras related GTP binding A
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane	Nucleus Cytoplasm Lysosome Lysosomal Membrane Cytosol EGO Complex GATOR1 Complex Gtr1-Gtr2 GTPase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activity Protein Binding GTP Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding
	Biological Process	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling	Apoptotic Process Cell Cycle Arrest Cell Death Cellular Response To Starvation Regulation Of Autophagy Negative Regulation Of Autophagy Regulation Of Macroautophagy Protein Ubiquitination Modulation By Virus Of Host Process Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein Localization Cellular Response To Amino Acid Stimulus Positive Regulation Of TORC1 Signaling
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes E3 ubiquitin ligases ubiquitinate target proteins Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)
Interacting Genes		10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W	6 interacting genes: DYNLT1 IL7R NOL8 RNF152 RPTOR RRAGC
Entrez ID		220441	10670
HPRD ID		11514	10205
Ensembl ID		ENSG00000176641	ENSG00000155876
Uniprot IDs		Q8N8N0	Q7L523
PDB IDs			5X6V 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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