UBA6 and JUNB

Data Source:
BioGRID (enzymatic study)

		UBA6	JUNB
Description		ubiquitin like modifier activating enzyme 6	JunB proto-oncogene, AP-1 transcription factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Chromatin Nucleoplasm Transcription Regulator Complex Transcription Factor AP-1 Complex
	Molecular Function	Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding FAT10 Activating Enzyme Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Learning Locomotory Behavior Protein Ubiquitination Protein Phosphopantetheinylation Amygdala Development Hippocampus Development Protein Modification By Small Protein Conjugation Dendritic Spine Development	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cytokine-mediated Signaling Pathway Osteoclast Differentiation Osteoblast Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)
Interacting Genes		16 interacting genes: HMBOX1 JUNB LMO2 OTUB1 SMAD9 UBC UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z	39 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG UBA6 UBE2I USP24 ZNF595 ZSWIM9
Entrez ID		55236	3726
HPRD ID		13341	01303
Ensembl ID		ENSG00000033178	ENSG00000171223
Uniprot IDs		A0AVT1 A1LT96	P17275 Q5U079
PDB IDs
Enriched GO Terms of Interacting Partners?
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