UBA6 and UBD

Data Source:
BioGRID (affinity chromatography technology, imaging technique, enzymatic study, two hybrid)

		UBA6	UBD
Description		ubiquitin like modifier activating enzyme 6	ubiquitin D
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Aggresome
	Molecular Function	Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding FAT10 Activating Enzyme Activity	Protein Binding Proteasome Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Learning Locomotory Behavior Protein Ubiquitination Protein Phosphopantetheinylation Amygdala Development Hippocampus Development Protein Modification By Small Protein Conjugation Dendritic Spine Development	Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To Interferon-gamma Response To Tumor Necrosis Factor Myeloid Dendritic Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Aggresome Assembly Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Neddylation
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 22412388) Fish- and plant-related diet ( 32066663) Height ( 25429064) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: HMBOX1 JUNB LMO2 OTUB1 SMAD9 UBC UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z	14 interacting genes: MAD2L1 NUB1 OTUB1 PDE9A PSMD4 SAE1 SRPK1 SRPK2 TGFBR1 UBA2 UBA6 UBE2D2 UBE2Z USP16
Entrez ID		55236	10537
HPRD ID		13341	09354
Ensembl ID		ENSG00000033178	ENSG00000213886
Uniprot IDs		A0AVT1 A1LT96	A0A1U9X8S6 O15205
PDB IDs			2MBE 6GF1 6GF2
Enriched GO Terms of Interacting Partners?
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