AKIRIN2 and HSD17B14

Data Source:
BioGRID (two hybrid)

		AKIRIN2	HSD17B14
Description		akirin 2	hydroxysteroid 17-beta dehydrogenase 14
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Repressor Complex	Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding Enzyme Binding Identical Protein Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Endopeptidase Activity Response To Lipopolysaccharide Positive Regulation Of Interleukin-6 Production Innate Immune Response Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II	Estrogen Biosynthetic Process Steroid Catabolic Process
Pathways			Estrogen biosynthesis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		10 interacting genes: CCDC85B FBXO7 HNRNPF HSD17B14 LNX1 MESD MYOZ3 NTAQ1 SORBS3 SPG21	24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B
Entrez ID		55122	51171
HPRD ID		12864	16801
Ensembl ID		ENSG00000135334	ENSG00000087076
Uniprot IDs		Q53H80 Q9NW35	A0A140VJH8 Q9BPX1
PDB IDs			1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK
Enriched GO Terms of Interacting Partners?
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