MAGOHB and PRPSAP1

Data Source:
BioGRID (two hybrid)

		MAGOHB	PRPSAP1
Description		mago homolog B, exon junction complex subunit	phosphoribosyl pyrophosphate synthetase associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)
Interacting Genes		73 interacting genes: ADAMTSL4 AMOTL2 BEND7 C18orf54 CALCOCO2 CARD10 CCDC102B CCDC106 CCDC33 DVL2 DVL3 EFHC2 FHL5 FXR1 GNPDA2 GOLGA2 GPANK1 HMG20A HSF2BP IHO1 IKZF1 IKZF3 INCA1 KRT40 KRT75 KRTAP1-1 KRTAP13-2 MID2 NDUFB7 PARD6B PAX7 PBX4 PKP2 PRPH PRPSAP1 PTPN21 RBAK RBM8A RBMX REL RUNDC3A SNW1 SPATA6 SPDYE4 STX11 TADA2A TCF4 TERF2 TERF2IP THAP7 TLE5 TRA2A TRA2B TRIM27 TRIM42 YWHAG ZBTB10 ZBTB42 ZFP14 ZFYVE1 ZNF19 ZNF250 ZNF398 ZNF426 ZNF438 ZNF446 ZNF449 ZNF547 ZNF566 ZNF57 ZNF620 ZNF774 ZNF835	9 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 PRPSAP2 UBE2I
Entrez ID		55110	5635
HPRD ID		08544	03151
Ensembl ID		ENSG00000111196	ENSG00000161542
Uniprot IDs		A0A023T6R1 F5H6P7 Q96A72	B4DP31 Q14558
PDB IDs		5XJC 5YZG 6ICZ 6QDV	2C4K
Enriched GO Terms of Interacting Partners?
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