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MAGOHB and PRPH
Data Source:
BioGRID
(two hybrid)
MAGOHB
PRPH
Description
mago homolog B, exon junction complex subunit
peripherin
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Exon-exon Junction Complex
Neuronal Cell Body
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 1 Spliceosome
Catalytic Step 2 Spliceosome
Cytoplasm
Intermediate Filament
Membrane
Axon
Perikaryon
Type III Intermediate Filament
Extracellular Exosome
Molecular Function
RNA Binding
Protein Binding
Structural Molecule Activity
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
MRNA Export From Nucleus
RNA Splicing
MRNA 3'-end Processing
Intermediate Filament Cytoskeleton Organization
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Prostate cancer (
21743467
)
Sural nerve amplitude potential (
30992453
)
Interacting Genes
73 interacting genes:
ADAMTSL4
AMOTL2
BEND7
C18orf54
CALCOCO2
CARD10
CCDC102B
CCDC106
CCDC33
DVL2
DVL3
EFHC2
FHL5
FXR1
GNPDA2
GOLGA2
GPANK1
HMG20A
HSF2BP
IHO1
IKZF1
IKZF3
INCA1
KRT40
KRT75
KRTAP1-1
KRTAP13-2
MID2
NDUFB7
PARD6B
PAX7
PBX4
PKP2
PRPH
PRPSAP1
PTPN21
RBAK
RBM8A
RBMX
REL
RUNDC3A
SNW1
SPATA6
SPDYE4
STX11
TADA2A
TCF4
TERF2
TERF2IP
THAP7
TLE5
TRA2A
TRA2B
TRIM27
TRIM42
YWHAG
ZBTB10
ZBTB42
ZFP14
ZFYVE1
ZNF19
ZNF250
ZNF398
ZNF426
ZNF438
ZNF446
ZNF449
ZNF547
ZNF566
ZNF57
ZNF620
ZNF774
ZNF835
36 interacting genes:
CDC37
CT55
DDX6
DES
FCHO1
INCA1
KIFC3
KRT14
KRT15
KRT16
KRT19
KRT20
KRT24
KRT27
KRT31
KRT75
LCA5L
LENG1
LMNB1
LNX1
MAGOHB
MYO5A
NXF1
PIAS2
PPP1R13B
PPP1R18
PRKAA2
PRPH2
PSMA1
TCEA2
TCP10L
TTC23
VIM
ZC4H2
ZMAT2
ZNF572
Entrez ID
55110
5630
HPRD ID
08544
01365
Ensembl ID
ENSG00000111196
ENSG00000135406
Uniprot IDs
A0A023T6R1
F5H6P7
Q96A72
B3KWQ6
P41219
PDB IDs
5XJC
5YZG
6ICZ
6QDV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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