PRPSAP1 and CAPN7

Data Source:
BioGRID (two hybrid)

		PRPSAP1	CAPN7
Description		phosphoribosyl pyrophosphate synthetase associated protein 1	calpain 7
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GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Nucleus Centrosome Cytosol Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding	Endopeptidase Activity Calcium-dependent Cysteine-type Endopeptidase Activity Protein Binding MIT Domain Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity	Positive Regulation Of Epithelial Cell Migration Self Proteolysis
Pathways			Degradation of the extracellular matrix
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)	Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 PRPSAP2 UBE2I	19 interacting genes: ARNT2 AXIN2 CEP63 CTBP2 GOLGA2 IFT88 IST1 MAD1L1 MAGED1 MDM4 PPP1R13B PRPSAP1 TNFAIP1 TRIM27 UBL7 VHL ZBTB9 ZFYVE19 ZNF655
Entrez ID		5635	23473
HPRD ID		03151	05908
Ensembl ID		ENSG00000161542	ENSG00000131375
Uniprot IDs		B4DP31 Q14558	Q7Z479 Q9Y6W3
PDB IDs		2C4K	2QFE
Enriched GO Terms of Interacting Partners?
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