MAGOHB and ZFYVE1

Data Source:
BioGRID (two hybrid)

		MAGOHB	ZFYVE1
Description		mago homolog B, exon junction complex subunit	zinc finger FYVE-type containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Phagophore Assembly Site Mitochondrion Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Lipid Droplet Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Extrinsic Component Of Omegasome Membrane Omegasome
	Molecular Function	RNA Binding Protein Binding	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Cellular Response To Starvation Negative Regulation Of Phosphatase Activity Macroautophagy Lipid Droplet Formation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			LDL cholesterol levels ( 32203549) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)
Interacting Genes		73 interacting genes: ADAMTSL4 AMOTL2 BEND7 C18orf54 CALCOCO2 CARD10 CCDC102B CCDC106 CCDC33 DVL2 DVL3 EFHC2 FHL5 FXR1 GNPDA2 GOLGA2 GPANK1 HMG20A HSF2BP IHO1 IKZF1 IKZF3 INCA1 KRT40 KRT75 KRTAP1-1 KRTAP13-2 MID2 NDUFB7 PARD6B PAX7 PBX4 PKP2 PRPH PRPSAP1 PTPN21 RBAK RBM8A RBMX REL RUNDC3A SNW1 SPATA6 SPDYE4 STX11 TADA2A TCF4 TERF2 TERF2IP THAP7 TLE5 TRA2A TRA2B TRIM27 TRIM42 YWHAG ZBTB10 ZBTB42 ZFP14 ZFYVE1 ZNF19 ZNF250 ZNF398 ZNF426 ZNF438 ZNF446 ZNF449 ZNF547 ZNF566 ZNF57 ZNF620 ZNF774 ZNF835	3 interacting genes: APP BCL2L1 MAGOHB
Entrez ID		55110	53349
HPRD ID		08544	12017
Ensembl ID		ENSG00000111196	ENSG00000165861
Uniprot IDs		A0A023T6R1 F5H6P7 Q96A72	Q9HBF4
PDB IDs		5XJC 5YZG 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
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