WIPI1 and KCTD15

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WIPI1	KCTD15
Description		WD repeat domain, phosphoinositide interacting 1	potassium channel tetramerization domain containing 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Trans-Golgi Network Cytosol Cytoskeleton Endosome Membrane Extrinsic Component Of Membrane Clathrin-coated Vesicle Phagophore Assembly Site Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Estrogen Receptor Binding Phosphatidylinositol-3-phosphate Binding Androgen Receptor Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding Identical Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Autophagy Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site IRE1-mediated Unfolded Protein Response Autophagy Of Nucleus Vesicle Targeting, Trans-Golgi To Endosome	Multicellular Organism Development Protein Homooligomerization
Pathways		Macroautophagy XBP1(S) activates chaperone genes	Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 19079260 19079261 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Dental caries (decayed and filled deciduous teeth) ( 31533690) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Disease progression in age-related macular degeneration ( 29346644) Major depressive disorder ( 23377640) Obesity-related traits ( 23251661) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 19079260)
Interacting Genes		5 interacting genes: AR ESR1 ESR2 KCTD15 PPA1	14 interacting genes: ATXN1 CYSRT1 ENSA KCTD1 NBPF19 NOTCH2NLA NOXA1 NTAQ1 REN TFAP2A TRIM27 TRIM55 TRIM63 WIPI1
Entrez ID		55062	79047
HPRD ID		08540	13765
Ensembl ID		ENSG00000070540	ENSG00000153885
Uniprot IDs		B4DX63 G5EA37 Q5MNZ9	Q96SI1
PDB IDs
Enriched GO Terms of Interacting Partners?
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