KCTD15 and ENSA

Data Source:
HPRD (two hybrid)

		KCTD15	ENSA
Description		potassium channel tetramerization domain containing 15	endosulfine alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Phosphatase Inhibitor Activity Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding
	Biological Process	Multicellular Organism Development Protein Homooligomerization	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Response To Nutrient Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Protein Dephosphorylation Regulation Of Insulin Secretion Cell Division
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors	MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 19079260 19079261 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Dental caries (decayed and filled deciduous teeth) ( 31533690) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Disease progression in age-related macular degeneration ( 29346644) Major depressive disorder ( 23377640) Obesity-related traits ( 23251661) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 19079260)	Albumin-globulin ratio ( 29403010) Chronotype ( 30696823) Coffee consumption ( 31959922) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082) Mean corpuscular volume ( 32888494) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 32888494 27863252) Morning person ( 30696823) Neutrophil percentage of granulocytes ( 27863252) Non-albumin protein levels ( 29403010) Pericardial adipose tissue adjusted for height and weight ( 27918534) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Sum eosinophil basophil counts ( 27863252) Urate levels ( 31578528)
Interacting Genes		14 interacting genes: ATXN1 CYSRT1 ENSA KCTD1 NBPF19 NOTCH2NLA NOXA1 NTAQ1 REN TFAP2A TRIM27 TRIM55 TRIM63 WIPI1	10 interacting genes: ABCC8 ACD ARIH2 ENO2 KCTD15 POT1 PSEN1 RAP2A SNCA SRPK2
Entrez ID		79047	2029
HPRD ID		13765	11927
Ensembl ID		ENSG00000153885	ENSG00000143420
Uniprot IDs		Q96SI1	O43768
PDB IDs
Enriched GO Terms of Interacting Partners?
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