KCTD15 and KCTD1

Data Source:
BioGRID (two hybrid)

		KCTD15	KCTD1
Description		potassium channel tetramerization domain containing 15	potassium channel tetramerization domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytosol Centriolar Satellite Intercellular Bridge
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Multicellular Organism Development Protein Homooligomerization	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors	Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 19079260 19079261 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Dental caries (decayed and filled deciduous teeth) ( 31533690) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Disease progression in age-related macular degeneration ( 29346644) Major depressive disorder ( 23377640) Obesity-related traits ( 23251661) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 19079260)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Sudden cardiac arrest ( 21658281)
Interacting Genes		14 interacting genes: ATXN1 CYSRT1 ENSA KCTD1 NBPF19 NOTCH2NLA NOXA1 NTAQ1 REN TFAP2A TRIM27 TRIM55 TRIM63 WIPI1	19 interacting genes: EPM2AIP1 EXOSC1 KCTD15 LMO1 LMO3 LNX1 MORF4L2 NTAQ1 PICK1 POLR1C PRKAA2 PSMA1 SDCBP TGM7 TRAPPC2 TRAPPC2B UBASH3A UBE2I ZBTB25
Entrez ID		79047	284252
HPRD ID		13765	11059
Ensembl ID		ENSG00000153885	ENSG00000134504
Uniprot IDs		Q96SI1	A0A024RC45 A0A2U3U043 Q719H9
PDB IDs			5BXB 5BXD 6S4L
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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