WIPI1 and PPA1

Data Source:
HPRD (two hybrid)

		WIPI1	PPA1
Description		WD repeat domain, phosphoinositide interacting 1	inorganic pyrophosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Trans-Golgi Network Cytosol Cytoskeleton Endosome Membrane Extrinsic Component Of Membrane Clathrin-coated Vesicle Phagophore Assembly Site Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding Estrogen Receptor Binding Phosphatidylinositol-3-phosphate Binding Androgen Receptor Binding Phosphatidylinositol-3,5-bisphosphate Binding	Magnesium Ion Binding Inorganic Diphosphatase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Autophagy Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site IRE1-mediated Unfolded Protein Response Autophagy Of Nucleus Vesicle Targeting, Trans-Golgi To Endosome	TRNA Aminoacylation For Protein Translation Phosphate-containing Compound Metabolic Process Diphosphate Metabolic Process
Pathways		Macroautophagy XBP1(S) activates chaperone genes	Cytosolic tRNA aminoacylation Pyrophosphate hydrolysis
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Blood protein levels ( 28240269)
Interacting Genes		5 interacting genes: AR ESR1 ESR2 KCTD15 PPA1	10 interacting genes: ERBB2 HSPB1 MCPH1 MTRNR2L1 SETDB1 SUMO4 TP53 UBC UNC119 WIPI1
Entrez ID		55062	5464
HPRD ID		08540	01527
Ensembl ID		ENSG00000070540	ENSG00000180817
Uniprot IDs		B4DX63 G5EA37 Q5MNZ9	Q15181 V9HWB5
PDB IDs			6C45 7BTN 7CMO
Enriched GO Terms of Interacting Partners?
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