PPA1 and WIPI1

Data Source:
HPRD (two hybrid)

		PPA1	WIPI1
Description		inorganic pyrophosphatase 1	WD repeat domain, phosphoinositide interacting 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Trans-Golgi Network Cytosol Cytoskeleton Endosome Membrane Extrinsic Component Of Membrane Clathrin-coated Vesicle Phagophore Assembly Site Membrane
	Molecular Function	Magnesium Ion Binding Inorganic Diphosphatase Activity	Signaling Receptor Binding Protein Binding Estrogen Receptor Binding Phosphatidylinositol-3-phosphate Binding Androgen Receptor Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phosphate-containing Compound Metabolic Process Diphosphate Metabolic Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Autophagy Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site IRE1-mediated Unfolded Protein Response Autophagy Of Nucleus Vesicle Targeting, Trans-Golgi To Endosome
Pathways		Cytosolic tRNA aminoacylation Pyrophosphate hydrolysis	Macroautophagy XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		10 interacting genes: ERBB2 HSPB1 MCPH1 MTRNR2L1 SETDB1 SUMO4 TP53 UBC UNC119 WIPI1	5 interacting genes: AR ESR1 ESR2 KCTD15 PPA1
Entrez ID		5464	55062
HPRD ID		01527	08540
Ensembl ID		ENSG00000180817	ENSG00000070540
Uniprot IDs		Q15181 V9HWB5	B4DX63 G5EA37 Q5MNZ9
PDB IDs		6C45 7BTN 7CMO
Enriched GO Terms of Interacting Partners?
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