HAUS8 and TXN2

Data Source:
BioGRID (two hybrid)

		HAUS8	TXN2
Description		HAUS augmin like complex subunit 8	thioredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytosol Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758)
Interacting Genes		14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS5 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 TXN2 USHBP1 ZG16B	79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32
Entrez ID		93323	25828
HPRD ID		11318	07161
Ensembl ID		ENSG00000131351	ENSG00000100348
Uniprot IDs		Q9BT25	Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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