PLEKHB2 and CD68

Data Source:
BioGRID (two hybrid)

		PLEKHB2	CD68
Description		pleckstrin homology domain containing B2	CD68 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Recycling Endosome Membrane	Lysosome Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Azurophil Granule Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding
	Biological Process	Regulation Of Cell Differentiation	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Aging Cellular Response To Nutrient Levels Autocrine Signaling Neutrophil Degranulation Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) IgA levels ( 28628107) Metabolic syndrome ( 31589552) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278)
Interacting Genes		49 interacting genes: ATF7IP BHLHE40 C1orf94 CD68 CDA CLDN19 DAZAP2 DCUN1D1 EMP1 EMP3 EPN1 EPN2 FAM168A FOXD4L3 GGA3 GJB2 GLIS2 HEY1 HEYL HGS HIVEP1 MAP3K1 MED25 MTURN NTAQ1 OTUB2 PIP4P1 PITX1 POGZ PROP1 RHBDD1 RPS27A SFT2D1 SNRPB STAM2 SYNGR1 TAX1BP1 TRARG1 UBA52 UBAC1 UBAP2 UBASH3A UBB UBC UBQLN2 UBXN6 UPF1 YOD1 ZFAND2A	12 interacting genes: ADRB2 AGR2 AQP6 CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6
Entrez ID		55041	968
HPRD ID		15144	01093
Ensembl ID		ENSG00000115762	ENSG00000129226
Uniprot IDs		A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7	P34810
PDB IDs		3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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