PLEKHB2 and NRGN

Data Source:
BioGRID (affinity chromatography technology)

		PLEKHB2	NRGN
Description		pleckstrin homology domain containing B2	neurogranin
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Recycling Endosome Membrane	Nucleus Cytosol Trans-Golgi Network Transport Vesicle Membrane Postsynaptic Density Axon Mitochondrial Membrane Neuronal Cell Body Dendritic Spine Head Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Calmodulin Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidic Acid Binding
	Biological Process	Regulation Of Cell Differentiation	Signal Transduction Nervous System Development Associative Learning Telencephalon Development Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Long-term Synaptic Potentiation
Pathways			Long-term potentiation Long-term potentiation
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 28991256 25056061 19571808 29483656 30285260)
Interacting Genes		49 interacting genes: ATF7IP BHLHE40 C1orf94 CD68 CDA CLDN19 DAZAP2 DCUN1D1 EMP1 EMP3 EPN1 EPN2 FAM168A FOXD4L3 GGA3 GJB2 GLIS2 HEY1 HEYL HGS HIVEP1 MAP3K1 MED25 MTURN NTAQ1 OTUB2 PIP4P1 PITX1 POGZ PROP1 RHBDD1 RPS27A SFT2D1 SNRPB STAM2 SYNGR1 TAX1BP1 TRARG1 UBA52 UBAC1 UBAP2 UBASH3A UBB UBC UBQLN2 UBXN6 UPF1 YOD1 ZFAND2A	6 interacting genes: CALM1 EIF5 GLP1R PRKCA PRKCB PRKCG
Entrez ID		55041	4900
HPRD ID		15144	03828
Ensembl ID		ENSG00000115762	ENSG00000154146
Uniprot IDs		A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7	A0A024R3M7 Q92686
PDB IDs		3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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