PLAAT2 and UBAC1

Data Source:
BioGRID (two hybrid)

		PLAAT2	UBAC1
Description		phospholipase A and acyltransferase 2	UBA domain containing 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Integral Component Of Membrane	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Phospholipase A2 Activity Protein Binding Phospholipase A1 Activity N-acyltransferase Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Protein Binding
	Biological Process	Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling N-acylphosphatidylethanolamine Metabolic Process	Protein Ubiquitination
Pathways		Acyl chain remodelling of PE	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: ASPH HPCAL1 NCALD UBAC1 UBQLN1 UBQLN2	34 interacting genes: AIRE APP ARRDC3 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B
Entrez ID		54979	10422
HPRD ID		13670	12170
Ensembl ID		ENSG00000133328	ENSG00000130560
Uniprot IDs		Q9NWW9	A0A140VK64 Q9BSL1
PDB IDs		4DPZ	2DAI
Enriched GO Terms of Interacting Partners?
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