UBAC1 and HOXA2

Data Source:
BioGRID (protein complementation assay)

		UBAC1	HOXA2
Description		UBA domain containing 1	homeobox A2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Determination Osteoblast Development Regulation Of Transcription By RNA Polymerase II Segment Specification Motor Neuron Axon Guidance Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 2 Development Rhombomere 3 Morphogenesis Brain Segmentation Middle Ear Morphogenesis Negative Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Viscerocranium Morphogenesis Cellular Response To Retinoic Acid
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Activation of anterior HOX genes in hindbrain development during early embryogenesis Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)	Chronic venous disease ( 28374850) Tonsillectomy ( 27182965 28928442)
Interacting Genes		34 interacting genes: AIRE APP ARRDC3 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B	6 interacting genes: DMPK MEIS1 NDE1 PPP1CB RCHY1 UBAC1
Entrez ID		10422	3199
HPRD ID		12170	05252
Ensembl ID		ENSG00000130560	ENSG00000105996
Uniprot IDs		A0A140VK64 Q9BSL1	O43364
PDB IDs		2DAI
Enriched GO Terms of Interacting Partners?
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