UBAC1 and PLAAT2

Data Source:
BioGRID (two hybrid)

		UBAC1	PLAAT2
Description		UBA domain containing 1	phospholipase A and acyltransferase 2
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GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Cytoplasm Cytosol Integral Component Of Membrane
	Molecular Function	Protein Binding	Phospholipase A2 Activity Protein Binding Phospholipase A1 Activity N-acyltransferase Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Protein Ubiquitination	Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling N-acylphosphatidylethanolamine Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Acyl chain remodelling of PE
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		34 interacting genes: AIRE APP ARRDC3 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B	6 interacting genes: ASPH HPCAL1 NCALD UBAC1 UBQLN1 UBQLN2
Entrez ID		10422	54979
HPRD ID		12170	13670
Ensembl ID		ENSG00000130560	ENSG00000133328
Uniprot IDs		A0A140VK64 Q9BSL1	Q9NWW9
PDB IDs		2DAI	4DPZ
Enriched GO Terms of Interacting Partners?
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