HPF1 and HMGN1

		HPF1	HMGN1
Description		histone PARylation factor 1	high mobility group nucleosome binding domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Histone Binding Poly-ADP-D-ribose Binding	DNA Binding Chromatin Binding Nucleosomal DNA Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Regulation Of Protein ADP-ribosylation Peptidyl-serine ADP-ribosylation	Transcription-coupled Nucleotide-excision Repair Chromatin Organization Positive Regulation Of DNA-templated Transcription, Elongation
Pathways			Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS			LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		15 interacting genes: EIF6 FBXO7 H1-0 H1-5 H2BC4 H3-3A H3-4 H3C1 HMGA1 HMGB1 HMGN1 HMGN2 HMGN4 PARP1 PARP2	21 interacting genes: CDC42 CHEK2 EP300 HMGN2 HPF1 IRF2 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 YWHAZ
Entrez ID		54969	3150
HPRD ID		07924	01231
Ensembl ID		ENSG00000056050	ENSG00000205581
Uniprot IDs		Q9NWY4	P05114 Q6NSG7
PDB IDs		6TX2 6TX3 6X0L 6X0M 6X0N
Enriched GO Terms of Interacting Partners?
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