PPM1G and FBXO38

Data Source:
BioGRID (two hybrid)

		PPM1G	FBXO38
Description		protein phosphatase, Mg2+/Mn2+ dependent 1G	F-box protein 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane	Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding
	Biological Process	Protein Dephosphorylation Cell Cycle Arrest Peptidyl-threonine Dephosphorylation	Adaptive Immune Response Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Neuron Projection Development SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Non-oily fish consumption ( 32066663) Takayasu arteritis ( 25604533) Triglyceride levels ( 31928498)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lung function (FEV1/FVC) ( 31453325) Lung function (FEV1/FVC) variance ( 31453325) Mean reticulocyte volume ( 32888494) Periodontal microbiota ( 22699663) Zinc levels ( 26025379)
Interacting Genes		10 interacting genes: FBXO38 GRIA3 H3-4 LRPAP1 MSL1 MTNR1B RPS6KA1 TERF1 TERF2 TERF2IP	8 interacting genes: ABL2 APP CREBBP KLF7 PPM1G RING1 SOX30 SUMO2
Entrez ID		5496	81545
HPRD ID		09237	09775
Ensembl ID		ENSG00000115241	ENSG00000145868
Uniprot IDs		O15355 Q6IAU5	Q6AZE0 Q6PIJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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