RNF113B and UBE2R2

Data Source:
BioGRID (two hybrid)

		RNF113B	UBE2R2
Description		ring finger protein 113B	ubiquitin conjugating enzyme E2 R2
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GO Annotations	Cellular Component	U2-type Spliceosomal Complex	Cytosol
	Molecular Function	Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	SnoRNA Splicing	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Metabolite levels ( 23823483)	Bipolar disorder ( 20351715) Body mass index ( 25673413) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: UBE2H UBE2L3 UBE2R2 UBE2U	27 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 GSC2 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 SDCBP UBA1 UBC
Entrez ID		140432	54926
HPRD ID		15745	15602
Ensembl ID		ENSG00000139797	ENSG00000107341
Uniprot IDs		Q8IZP6	Q712K3
PDB IDs		2CSY	6NYO
Enriched GO Terms of Interacting Partners?
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