PLPPR1 and PLN

Data Source:
BioGRID (two hybrid)

		PLPPR1	PLN
Description		phospholipid phosphatase related 1	phospholamban
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Integral Component Of Plasma Membrane	Mitochondrion Endoplasmic Reticulum Membrane Mitochondrial Membrane Vesicle Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Calcium Ion-transporting ATPase Complex
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity Lipid Phosphatase Activity	Enzyme Inhibitor Activity Protein Binding ATPase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Nervous System Development Phospholipid Dephosphorylation	Regulation Of The Force Of Heart Contraction Calcium Ion Transport Notch Signaling Pathway Blood Circulation Regulation Of Heart Contraction Response To Zinc Ion Negative Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of ATPase Activity Response To Insulin Response To Testosterone Negative Regulation Of Catalytic Activity Cardiac Muscle Tissue Development Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transport Relaxation Of Cardiac Muscle Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Binding Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways		Lysosphingolipid and LPA receptors	Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Hip circumference adjusted for BMI ( 28552196)	Atrial fibrillation ( 28416818 30061737) Cardiac structure and function ( 19584346) QRS complex (Sokolow-Lyon) ( 27659466) QRS duration ( 27577874 27659466) QT interval ( 23166209 24952745 19305408 19305409 19587794 29874175) Resting heart rate ( 27798624)
Interacting Genes		5 interacting genes: LEPROT PLN SERP1 SLC30A2 TMPPE	64 interacting genes: ARL13B ASGR2 ATP2A1 ATP2A2 ATP6V0E1 BCL2L13 BIK CD53 CLDN7 CLEC2D CPLX4 CREB3 CREB3L1 DMPK DVL3 EDA ELOVL4 FAM209A FKBP8 FNDC9 GJA8 GPR152 GPR37L1 GPX8 HIBADH HSD17B13 KIR2DL3 LDLRAD1 LSMEM2 MFF MFSD5 MGST2 MGST3 MS4A7 MTIF3 MUC1 PLPPR1 PPP1R3A PRKACA RTN3 S100A1 SAR1A SDC3 SIT1 SLC14A2 SLC30A8 SLC34A2 SLC35C2 SLC39A2 SLN SPACA1 SPAG4 STX1A STX2 TMEM106C TMEM179B TMEM205 TMEM31 TMEM45A TMEM45B TMEM52B TMEM79 TMEM86B TMPRSS2
Entrez ID		54886	5350
HPRD ID		17906	01395
Ensembl ID		ENSG00000148123	ENSG00000198523
Uniprot IDs		A0A024R154 Q8TBJ4	P26678 Q5R352
PDB IDs			1K9N 1KCH 1PLN 1PLP 1PSL 1ZLL 2HYN
Enriched GO Terms of Interacting Partners?
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