FNBP1L and USP13

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FNBP1L	USP13
Description		formin binding protein 1 like	ubiquitin specific peptidase 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Lipid Binding Cadherin Binding GTPase Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Vesicle Budding From Membrane Autophagy Signal Transduction Membrane Invagination Vesicle Organization Vesicle Transport Along Actin Filament Positive Regulation Of Filopodium Assembly Cilium Assembly Membrane Organization Clathrin-dependent Endocytosis Plasma Membrane Tubulation	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Protein Phosphopantetheinylation Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Clathrin-mediated endocytosis	Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Triglyceride levels ( 29403010)
Interacting Genes		6 interacting genes: ACP1 CDC42 DNM2 SGSM2 USP13 WASL	18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		54874	8975
HPRD ID		12317	04666
Ensembl ID		ENSG00000137942	ENSG00000058056
Uniprot IDs		B4DSI7 Q5T0N5	A0A0A6YZ17 Q92995
PDB IDs			2L80 2LBC
Enriched GO Terms of Interacting Partners?
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