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USP13 and MYO15A
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
USP13
MYO15A
Description
ubiquitin specific peptidase 13
myosin XVA
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Cytoplasm
Actin Cytoskeleton
Myosin Complex
Vesicle
Stereocilium
Extracellular Exosome
Actin-based Cell Projection
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
Ubiquitin-like Protein Ligase Binding
Chaperone Binding
Proteasome Binding
BAT3 Complex Binding
Lys48-specific Deubiquitinase Activity
Microfilament Motor Activity
Calmodulin Binding
ATP Binding
Actin-dependent ATPase Activity
Actin Filament Binding
Biological Process
Regulation Of Transcription, DNA-templated
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Cell Population Proliferation
Regulation Of Autophagy
Protein Deubiquitination
Protein Phosphopantetheinylation
Melanocyte Differentiation
Protein K29-linked Deubiquitination
Protein K6-linked Deubiquitination
Protein Stabilization
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Positive Regulation Of ERAD Pathway
Maintenance Of Unfolded Protein Involved In ERAD Pathway
Actin Filament Organization
Sensory Perception Of Sound
Vesicle Transport Along Actin Filament
Pathways
Ub-specific processing proteases
Regulation of PTEN stability and activity
Drugs
Diseases
Deafness, autosomal recessive
GWAS
Change in neurofilament light levels (
31295725
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Obesity-related traits (
23251661
)
Red blood cell count (
32888494
)
Schizophrenia (
25056061
)
Serum folate levels (
29953918
)
Interacting Genes
18 interacting genes:
AMFR
BAG6
DAZAP2
DVL1
FNBP1L
FUNDC2
LAPTM5
MCL1
MDC1
MRPL20
MYO15A
SIAH2
SPRR2C
TRIM55
TRIM63
UBC
UBL4A
UIMC1
4 interacting genes:
EPS8
FASLG
USP13
WHRN
Entrez ID
8975
51168
HPRD ID
04666
04049
Ensembl ID
ENSG00000058056
ENSG00000091536
Uniprot IDs
A0A0A6YZ17
Q92995
Q9UKN7
PDB IDs
2L80
2LBC
6KZ1
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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