USP13 and MRPL20

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	MRPL20
Description		ubiquitin specific peptidase 13	mitochondrial ribosomal protein L20
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Protein Phosphopantetheinylation Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway	Ribosomal Large Subunit Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30578418) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1	11 interacting genes: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ERCC6 ITSN1 OXA1L TP53BP2 USP13
Entrez ID		8975	55052
HPRD ID		04666	14746
Ensembl ID		ENSG00000058056	ENSG00000242485
Uniprot IDs		A0A0A6YZ17 Q92995	Q9BYC9
PDB IDs		2L80 2LBC	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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