MFSD6 and GPX8

Data Source:
BioGRID (two hybrid)

		MFSD6	GPX8
Description		major facilitator superfamily domain containing 6	glutathione peroxidase 8 (putative)
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Lumen Integral Component Of Membrane
	Molecular Function	Protein Binding	Peroxidase Activity Glutathione Peroxidase Activity Protein Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification
Pathways			Detoxification of Reactive Oxygen Species
Drugs			Glutathione Glutathione disulfide
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)	Cocaine dependence ( 31212010)
Interacting Genes		36 interacting genes: ADIPOQ ALG8 APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 GJA8 GJB2 GPR152 GPR42 GPX8 LY6E MFSD4B NKG7 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SMIM1 SSMEM1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2	152 interacting genes: - AGTRAP AIG1 ALG8 APOC3 APOD AQP1 AQP2 AQP3 ASGR1 ASPH BCL2L2 BET1 BIK BMP10 BNIP2 BTN2A2 C14orf180 C1GALT1 CACNG1 CD302 CD53 CD81 CDIPT CDS2 CFHR5 CHST1 CLDN19 CLEC1A CLEC2A CMTM5 CNIH1 CNIH3 COL4A5 COL8A2 CORIN CYB561 CYB561A3 CYB561D2 DNAJC30 DOLK EDDM3B ERG28 ERO1A FA2H FAM3C FAXDC2 GET3 GOSR2 GPR151 GPR37L1 GRINA GYPA HHATL HMOX2 IGFBP5 INSIG2 KIR2DL3 KLRG1 LAPTM4B LEPROTL1 LHFPL5 LNPEP LPAR3 MAN2B2 MARCHF2 MARCHF5 MFSD5 MFSD6 MGST2 MGST3 MIP MMD MYADML2 NEU1 NINJ1 NIPAL3 NKG7 NRM OCLN PAEP PAQR5 PAQR6 PGAP2 PLLP PLN PLP2 PLPP4 PLPP6 PNLIPRP1 PRB1 RBFA RND1 RTP2 SCARB2 SCARF1 SCD SEC22B SELENOK SERINC1 SERINC2 SERP1 SERTM1 SFTPC SGMS2 SLC13A3 SLC30A3 SLC34A3 SLC35A1 SLC35B4 SLC41A2 SMAGP SNORC ST6GAL2 STX3 STX8 SYT15 TF THBD TIMMDC1 TM4SF4 TMBIM6 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14B TMEM19 TMEM218 TMEM229B TMEM243 TMEM254 TMEM42 TMEM50B TMEM60 TMEM86B TMEM97 TMPRSS4 TMUB2 TRAM1L1 TSPAN33 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1L1 VSTM1 VTI1B YIF1A YIPF6 ZDHHC22
Entrez ID		54842	493869
HPRD ID		13369	17416
Ensembl ID		ENSG00000151690	ENSG00000164294
Uniprot IDs		Q6ZSS7	B4DPY0 E7ETY7 J3KNB5 Q8TED1
PDB IDs			3CYN 3KIJ
Enriched GO Terms of Interacting Partners?
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