MFSD6 and TMEM258

Data Source:
BioGRID (two hybrid)

		MFSD6	TMEM258
Description		major facilitator superfamily domain containing 6	transmembrane protein 258
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	Protein N-linked Glycosylation
Pathways
Drugs
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)	Asthma ( 31959851 31619474) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil counts ( 32888494) Glycerophospholipid levels ( 26068415) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Male-pattern baldness ( 28196072) QRS duration ( 27659466) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) Resting heart rate ( 27798624) Reticulocyte count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		36 interacting genes: ADIPOQ ALG8 APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 GJA8 GJB2 GPR152 GPR42 GPX8 LY6E MFSD4B NKG7 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SMIM1 SSMEM1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2	4 interacting genes: ARL6IP1 IER3IP1 MFSD6 UBQLN1
Entrez ID		54842	746
HPRD ID		13369	12602
Ensembl ID		ENSG00000151690	ENSG00000134825
Uniprot IDs		Q6ZSS7	P61165
PDB IDs			6S7O 6S7T
Enriched GO Terms of Interacting Partners?
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