BEST2 and FXYD3

Data Source:
BioGRID (two hybrid)

		BEST2	FXYD3
Description		bestrophin 2	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Chloride Channel Complex	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Molecular_function Chloride Channel Activity Protein Binding	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	Sensory Perception Of Smell Biological_process Membrane Depolarization Chloride Transmembrane Transport	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Stimuli-sensing channels	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL MFSD5 PNLIPRP1 RFT1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		54831	5349
HPRD ID		09548	05410
Ensembl ID		ENSG00000039987	ENSG00000089356
Uniprot IDs		Q8NFU1	Q14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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