BEST2 and RFT1

Data Source:
BioGRID (two hybrid)

		BEST2	RFT1
Description		bestrophin 2	RFT1 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Chloride Channel Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Chloride Channel Activity Protein Binding	Protein Binding
	Biological Process	Sensory Perception Of Smell Biological_process Membrane Depolarization Chloride Transmembrane Transport	Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Transport Glycolipid Translocation
Pathways		Stimuli-sensing channels	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective RFT1 causes RFT1-CDG (CDG-1n)
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Crohn's disease ( 28067908) Feeling worry ( 29500382) Height ( 23563607 31562340) High density lipoprotein cholesterol levels ( 31928498) Hip circumference adjusted for BMI ( 25673412) Immune reponse to smallpox (secreted IL-2) ( 22610502) Schizophrenia ( 23974872) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 30297969)
Interacting Genes		16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL MFSD5 PNLIPRP1 RFT1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B	12 interacting genes: AQP6 BEST2 CNR2 CREB3L1 ERGIC3 MUC1 NEDD4 PSMA3 RNF144A TMX2 TNS2 TSPAN12
Entrez ID		54831	91869
HPRD ID		09548	15239
Ensembl ID		ENSG00000039987	ENSG00000163933
Uniprot IDs		Q8NFU1	Q96AA3
PDB IDs
Enriched GO Terms of Interacting Partners?
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